The research, conducted by researchers from the University of Lisbon, Portugal, and the University of Washington, Seattle, studied the possible neurological effects of dental amalgam tooth restorations.
Dental amalgam contains elemental mercury combined with other metals such as silver, copper, tin and zinc to form a safe, stable alloy. For generations, it has been used to fill decayed teeth that might otherwise have been lost.
In the seven-year long study, the researchers studied 507 children aged 8 through 12 years who received either amalgam or resin-based composite fillings.
The research team conducted routine clinical neurological examinations to assess two types of neurological signs: hard (indicating damage to specific neural structures) and soft (subtle signs of central nervous system dysfunction that likely point to immature sensory-motor skills rather than to any structural damage in the brain).
